Polyclonal gammopathy is your body’s strong overproduction of antibodies to defend itself from an unknown cause. It is often associated with infections, cancer, or chronic diseases. Diseases of the liver and collagen commonly lead to polyclonal gammopathy. Other diseases or infections which arise from polyclonal gammopathy include scleroderma, primary biliary cirrhosis, polymyositis, rheumatoid arthritis, chronic fungal infections, chronic bronchitis, systemic lupus eryhtmatous, tuberculosis, infectious hepatitis, and chronic active hepatitis{http://www.healthcaretip.com/2019/04/polyclonal-gammopathy.html}.
Polyconal gammopathy does not have symptoms other than the symptoms associated with the underlying cause. This is why it is imperative to find the underlying cause and begin treating it as soon as possible. Symptoms appearing may be associated with the underlying cause. But some common symptoms which appear in almost all infections and diseases are stress, fatigue, depressed mood, pain in the specified area of infection, and anxious mood. Remaining symptoms are specified by the underlying disease or infection{https://www.healthcaretip.com/2019/04/polyclonal-gammopathy.html}.
Certain conditions put you at higher risk for developing polyclonal gammopathy, including:
Autoimmune conditions such as lupus, rheumatoid arthritis or Sjogren’s syndrome.
Blood disorders (including sickle cell anemia).
Blood cancers such as leukemia and lymphoma.
Cancer (kidney cancer, liver cancer, lung cancer and ovarian cancer).
Infections such as HIV, malaria, mononucleosis, pneumonia and tuberculosis.
Liver disease (including autoimmune hepatitis, cirrhosis and viral hepatitis). {https://my.clevelandclinic.org/health/diseases/22403-polyclonal-gammopathy }.